Matthew McConaughey and Jared Leto both took home shiney gold statues at this year’s Oscars.

The actors of “Dallas Buyers Club,” the best picture-nominated drama about AIDS in 1980s Texas, were honored by the Academy of Motion Pictures Arts and Sciences.

McConaughey and Leto won best actor and best supporting actor for their roles in the film as a heterosexual rodeo rat (McConaughey) and a transgender drug addict (Leto) united by HIV.

“Thirty-six million people who have lost the battle to AIDS and to those of you out there who have ever felt injustice because of who you are or who you love, tonight I stand here in front of the world with you and for you,” said Leto is his acceptance speech.

“Dallas Buyers Club” took two decades to get made after countless executives balked at financing such a tale. McConaughey lost 50 pounds for the role of Ron Woodruff, a cowboy who fought the U.S. government during the AIDS epidemic of the 1980s to provide patients with medicines he imported from foreign countries.

In his acceptance speech, McConaughey, 44, thanked “God, because that's who I look up to. He's graced my life with opportunities that I know are not of my hand or any other human hand. He has shown me that it's a scientific fact that gratitude reciprocates.”

McConaughey was chosen over other nominees Bruce Dern for “Nebraska,” Leonardo DiCaprio for “The Wolf of Wall Street,” Chiwetel Ejiofor for “12 Years a Slave,” and Christian Bale for “American Hustle.”

“12 Years a Slave” – a griping drama about pre-civil war America -- won best picture.

Elsewhere at the Oscars, lesbians Robin Roberts and Ellen DeGeneres conducted many interviews throughout the evening with DeGeneres hosting the proceedings. The 2014 show was the 86th broadcast of the Academy Awards.